1 videos available in lipid disorders
50:06
Lipodystrophy
Abhimanyu Garg, MD, and Zehra Tekin, MD, give an insightful case discussion on lipodystrophy. Learn how to diagnose and treat this endocrine disorder.
Key Learning Points:
- Look beyond BMI when diagnosing lipodystrophy. Patients may have a normal BMI but severe metabolic complications. Key signs include muscular limbs, loss of subcutaneous fat, and fat accumulation in the face, neck, and trunk.
- Recognize the importance of family history and genetic testing. Familial partial lipodystrophy is often inherited in an autosomal dominant pattern. LMNA is the most common gene discussed, followed by PPARG. Genetic testing helps confirm the diagnosis.
- Severe hypertriglyceridemia is a major concern. Extremely elevated triglycerides can cause recurrent acute pancreatitis and increase long-term cardiovascular risk. Early recognition and treatment are essential.
- +2 more points...
2026
Oct 31, 2026